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HomeHEALTHYDoes Genetics Play a Role in Eczema?

Does Genetics Play a Role in Eczema?

Eczema is a term used to describe skin conditions that cause inflammation and irritation. According to studies, eczema is caused by genetic changes, immune issues, and environmental factors.

 

Studies also reveal that one in fifty adults and one in five children suffer from eczema. It is true that anyone can develop eczema. However, studies show that people with allergies, asthma and eczema are more likely to have children with eczema.

 

Eczema, heredity

Eczema is a common condition. According to a 2015 investigation, the chances of getting eczema are about 75% if you have a family history.

 

The information that is needed to produce protein comes from the genes. Every human being has two copies, one from each parent. If you inherit a defective (mutated gene) from either of your parents, then your chances of developing eczema are increased.

 

Studies suggest that eczema may be genetically influenced by many genes, even though this is not known. In some cases, you may inherit just one gene from your parents that causes eczema.

 

CARD11 is a good example of a gene like this. This gene contains all the information needed to make proteins for immune effector cells, called lymphocytes. These immune effector cells protect the body from diseases.

 

 

A mutation or error within the CARD11 gene may lead to atopic skin eczema, due to the defectiveness of the immune effectors. Studies have shown that about five CARD11 gene mutations can be found in people with atopic skin conditions. According to research conducted in 2017, eczema may occur when only one copy of CARD11 is mutated.

 

KIF3A, another essential gene for eczema, is also present. This gene codes proteins responsible for cell signals and transportation. A 2020 study found that genetic variations in KIF3A could increase your risk of developing eczema. The skin is losing water, and the skin barrier is weakening.

 

Filaggrin is one of the most important proteins in skin hydration. The gene that codes for this protein, profilaggrin, is the FLG gene. Profilaggrin is the source of the protein filaggrin.

 

About 20-30% people with FLG mutations developed atopic skin eczema. This is an indication of a connection between FLG and atopic skin conditions.

 

Can someone spread eczema on me?

Eczema is not contagious. This means that touching someone who has eczema won’t cause you to get it.

 

People with eczema are more likely to contract diseases due to the breakdown of their skin barrier. Eczema can lead to skin infections that spread.

 

Herpes simplex virus type 1 (HSV-1) can cause eczema in people with atopic eczema. Blisters may appear on the surface of the skin and may bleed or drip. Eczema is contagious.

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